New biomedical technologies to support the development of medicine and basic biology. Indispensable

Li Zhuang reproduced
New biomedical technologies to support the development of medicine and basic biology. Indispensable to the development of modern medical biology biomedical technology progress. From the microscope, centrifuge, electrophoresis, isotope, X-Ray to the present high-throughput, sensitivity analysis, sequencing, recombination, cloning, transfer, chip, fluorescence imaging, nanotechnology, synthetic, information technology, without a non-leading rohrlux advances in medical biology now. No biomedical technology innovation and progress, there will be now and in the future development of medical biology. Here we from Science, Nature, PNAS, Cell and abroad rohrlux on the website excerpts biomedical 2008-2009 more than 120 new biomedical technologies, for your reference. In addition, our special report on CMBI text column also reported rohrlux that new technologies (379), cardiovascular imaging (368), the comet was measured (366), fluorescent protein (363), artificial life (331), methodology (303), Systems Biology (272), nano-medicine rohrlux (271), rohrlux Biomarkers (267), Antibody Engineering rohrlux (251), Cellular and Molecular Biology (240), live cell imaging (226), combinatorial chemistry (216), the virtual cell (199), tissue engineering (186), DNA vaccines (176), biochips (122), nearly 20 did a special report, about 7,000 documents. From these reports, we can see emerging biomedical technology, by leaps and bounds. Toward a higher, more refined, more micro, rohrlux faster, more sensitive, more convenient, more economical, more practical direction; towards multi-disciplinary, multi-technology, cross-cutting direction; towards a high-throughput, multi-molecule, multi- channel, multi-factor, multi-site comprehensive analysis of complex systems develop in the direction; towards the living, dynamic, full-featured, the whole process rohrlux of direction, so that biomedical technology into the 21st century the most critical and the core, the most widely used technology It is the development of a new generation of medical biology, creating the necessary conditions! A deeper and more great new era in the life sciences is coming! Become rohrlux the world's economic, social and scientific development the focus of competition! We must catch up, vigorously strengthen biomedical research and development of new technologies. This is our urgent task! This decade of biomedical achieved rapid development, every year in the world of SCI papers published has nearly ten thousand articles. However, we have to point out, can not help worrying, these achievements and development is still fragile, is not solid. Our research and development is the introduction of the technology used, the instrument is imported, the reagent is abroad, medicines, equipment, patents are the others! In our modern biological extract hundreds of new technologies which, in particular, is the key and core technology, the country is almost a no! We can not build our biomedical developments on the beach! Our eyes can not just stare at a few of SCI papers, and to put new technology research and development! Development rohrlux so that we will be rewarding, have only basis for sustainable rohrlux development! Also in order to truly achieve our biomedical services for social and economic purposes! This is truly implement the scientific concept of development! Biomedical field to implement the scientific concept of development, we must vigorously strengthen biomedical research and development of new technologies, we have our own new technology, new equipment, new equipment, new reagents, new medicines to meet the development of our country and the people of biomedical disease prevention and treatment needs! Meanwhile also the world development of life sciences to make our contribution! Also in order to fundamentally solve the problem of medical treatment is difficult and expensive. Because we are now using diagnostic equipment, medical equipment, essential drugs are critical reagents and abroad and buy! Biomedical research and development of new technologies must be: first, to correct for the "new technology" concept and attitudes necessary to fully understand the development of new technology in medical biology in the role and status, to completely change the weight papers, light science rohrlux and technology thoughts; Second, to develop a professional biomedical research institutions new technology institutes and schools, rohrlux to introduce and develop biomedical technology research and development of specialized personnel; Third, we should seriously and factual summary of twenty years to the National Bio-Tech Program (863) of the experiences and lessons more effectively to strengthen investment in new technologies, medical biotechnology and funding; Fourth, we must accelerate the transformation of research, development and application, so that the patent can not be merely the head of the paper , and to implement into the product; Fifth, we should strongly encourage and subsidize individuals and research institutes and enterprises, independent development of new technologies, new methods, the production of new equipment, new equipment, new reagents, new equipment and new drugs; Section Sixth, to strengthen rohrlux domestic and international cooperation, the introduction, rohrlux digestion, transformation and restructuring rohrlux of foreign advanced technology, making it with its own intellectual property rights, our country can continue to use, production and flowering of new technologies, rohrlux rather than simply buying and applications. We have completely changed our medical biotechnology backward status quo! Support to truly become the 21st century economic, social and scientific development of the pillar! This is our field of pharmaceutical biotechnology implement the scientific concept of development to the task. Here are more than 120 world 2008-2009 Pharmaceutical Biotechnology new technologies, more medical and biological technologies available "METHOD-" and "BIOTECH-" and other words in CMBI query. Single-molecule imaging microscopy single molecule imaging technology, is now moving rohrlux in the body, living cells, high sensitivity, multi-molecular, high-throughput direction. There fluorescence microscopy, rohrlux suppository tablets microscope, magneto-optical tweezer (tweezer), atomic force microscopy, single molecule mechanics spectral microscope and so on. They not only living cells can be measured, single molecules, multi-molecular positioning and dynamic changes in the protein can be measured rohrlux with the protein, DNA and DNA, DNA and proteins relationship changes. It will revolutionize modern biology (Nature. 2008.5.29; Nature Method, 2009.3.1; 2009.3.22) for biological research robot UK Aberystwyth University systems biology and computer scientists Clare A, etc., invented one kind of research can be carried out independently of the robot, called the Automation of science, also known as "Adam." It can be designed independently, reasoning, experiments and analysis of results. Yeast and has completed the analysis of gene structure and function. This robot can simultaneously multi-project and multi-subject research rohrlux and analysis. It is a major breakthrough in artificial intelligence research (Science, 2009.4.3). MicroRNA-mediated pluripotent stem cells regenerate American UCSF Medical Center embryonic stem cell scientists apply a specific microRNA (miR-291-3P), instead of through liposome mediated by retroviral OCT4, Sox2 and KIF4 to skin cells can be successfully generate pluripotent stem cells, can avoid cancer risk (Nature Biotech, 2009.4). Combo antibody generally an antibody with an antigen rohrlux binding only recently Genentech, United rohrlux States, to develop a combo antibody, rohrlux It can be combined with VEGF, but also with the EGF-R (HER-2) combined with the Cancer treatment is important (Science, 2009.3.20). Nano proteomic immunoassay (NIA) Department of Pathology, Stanford University School of Medicine scientists developed a trace, sensitive detection of small samples suitable for clinical proteome analysis technology called Nano proteomic immunoassay (Naofluidic Proteomic Immunoassay, NIA). It is just a sample of blood or needles size can measure a variety of cancer-related protein expression and phosphorylation levels. For cancer diagnosis can be accurately and guide treatment (Nature Medicine, 2009.4.12). Assess the risk of cardiovascular and cerebrovascular attack how to assess new tools with non-ST elevation myocardial infarction in patients with risk of cardiovascular sector has been a problem. Duke University, the University of Washington and cardiovascular scientists, through the analysis of clinical data, a new assessment tool. It includes heart rate, blood pressure, RBC, creatinine clearance rate eight factors that can accurately assess the risk of cardiovascular disease rohrlux onset (Circulation, 2009.4.15). In addition, U.S. Baylor College of Medicine has also developed a new evaluation method for stroke treatment effect (Strok, 2009.3.12). Wearable Defibrillator English Cheshir pharmaceutical company recently developed a defibrillator can be worn on the body, which can monitor and treat anytime heart attacks and sudden death, called Lifevest (Med News Today, 2009,3.18) . Recently, the U.S. company has developed a Biotronik implantable defibrillator Lumax540, has been approved by the FDA for patients with heart failure rohrlux monitoring and treatment (Med News Today, 2009.4.15). "Brainwashing" material SUNY Sacktor TC and Memory Research discovered a molecule closely related PKMzeta, looking rohrlux into a series of related chemical substances, they can open and close the human memory, rohrlux It can prevent senile dementia and Some memory problems, but also inhibit some of the information rohrlux stored in the brain and memory, eliminating the fear of human suffering and bad habits, reduce the pressure of (Global Science, 2009.4.15). Tsinghua University, Department of Materials Cui broken bone regeneration Fuzhai study group and PLA General Hospital co-parsing process of bone formation and materials, rohrlux developed a nanocrystalline calcium phosphate gel material, can broken bone repair and regeneration (biological pass, 2009.4.16) . Watch like a portable blood pressure monitor U.S. scientists have developed a new portable blood pressure monitor can be like a watch band on your wrist to monitor people's blood pressure (Science and Technology rohrlux Daily, 2009.4.16). rohrlux Tumor growth, three-dimensional video U.S. Amgen has developed a three-dimensional video images of tumor growth, angiogenesis was observed to reveal rohrlux tumor nutrient supply, the process of tumor growth and metastasis, and clear images (Wired, 2009.4.15). Assess the effect of cancer chemotherapy new methods generally assess the effect of chemotherapy requires three months. Cancer Institute of the United States proposed a UCLA with PET / CT evaluation of new methods. As long as one week to assess the effect of chemotherapy (Clin Cancer, 2009.4.15). rohrlux In vivo DNA assembler (Assembler) U.S. Department of Bioengineering, University of Illinois rohrlux developed a DNA Assembler. It uses recombinant DNA methods and Yeast step conversion technology, you can quickly build in the body born of the path, it is synthetic biology, metabolic engineering and functional genomics research, providing a new and powerful tool (Nucleic Acid Res, 2009.2) . Cell division, Building Systems MIT scientists using different cell surface rolling different capacities, cell division designed and developed a building system. It can not only of building cells, stem cells can also be of buildings, can also be used for cell free concentrated. The method is simple, without expensive equipment, and security does not damage cells (Nono Letter, 2008.3). University of Melbourne, Australia, micro motor micro and nano lab developed a micro-motor, only 250μm. rohrlux It can enter the bloodstream, transmit intravascular images, clear plaque and thrombus, biopsy and fixed drug delivery (easy network exploration, 2009.1.22). Artificial Neural Networks - dimensional one hundred million hybrid chip resistors rohrlux to the University of California Berkeley campus and imprint lithography applications at HP Labs, the one hundred million resistor crossbar stacked on a CMOS logic circuit having a density of adult cortical synapses 10 times, you can simulate the human neural network transmission and learning (biological pass, 2008.12.3). Preparation of a new method of protein chip UK Manchester Interdisciplinary Center for Biological scientists have developed a way to faster and better rohrlux preparing functional protein chip the new method. Tag them using specific for protein modification, a variety of active protein allows fast, efficient, without losing the feature fixed on the chip, without the need for protein purification. It is a new revolution in protein chips (JACS, 2008.8.22). MicroRNA-mediated pluripotent stem cells regenerate American UCSF Medical Center embryonic stem cell scientists apply a specific microRNA (miR-291-3P), instead rohrlux of through liposome mediated by retroviral OCT4, Sox2 and KIF4 to skin cells can be successfully generating pluripotent stem